Episode 073: Management of Early Stage Diffuse Large B-Cell Lymphoma (DLBCL)

This week, we continue our conversation about DLBCL, this time focusing our attention on the management of early stage disease.

If you have not done so, we highly recommend you listen to our hemepath series before proceeding with this episode. Furthermore, if you have not listened to the introduction to DLBCL episode (Episode 072), we highly recommend doing so, as we will be building on these basics this week.

Episode 072: Introduction to Diffuse Large B-Cell Lymphoma (DLBCL)

This week, we kick off a new series focusing on diffuse large B-cell lymphoma. In this first episode, we discuss the basics that everyone needs to understand before diving into the management of this disease.

Episode 071: Heme Consults Series: Heparin-induced thrombocytopenia (A deeper dive!)

We revisit a topic covered previously as part of our “Heme/Onc Emergencies” series: heparin-induced thrombocytopenia (HIT) in Episode 017. As part of our return, we dive deeper into the pathophysiology, principles of diagnosis, and management of HIT to help you to better understand how to approach the question of “is this HIT?” as a Hematology consultant and, more importantly, how to guide management based on your index of suspicion.

Episode 070: Heme Consults Series: Von Willebrand Disease, Part 2

This week in our hematological consultation series, we continue our discussion on von Willebrand disease (vWD), this time focusing on the type 2 subtypes and we also discuss management.

In case you missed it, we recommend checking out episode 069 for Part I of this vWD series, covering taking a bleeding history and about Type 1 and Type 3 disease.

Episode 069: Heme Consults Series: Von Willebrand Disease, Part 1

We resume our hematological consultation series with an overview of von Willebrand disease (vWD), the most common inherited bleeding disorder. In this episode, we talk about the initial steps we should take to evaluate suspected von Willebrand disease and how to differentiate the various subtypes. We will focus on vWD type 1 and 3! Be sure to tune in next week as we discuss vWD type 2 and management.

Episode 068: Breast Cancer Series, Pt. 13- Metastatic Triple Negative Breast Cancer

This week, we complete our breast cancer series, focusing on triple-negative breast cancer (TNBC). The last few months have been quite the journey! Please continue to refer to our shownotes to help navigate this complex disease treatment paradigm.

Episode 067: Breast Cancer Series, Pt. 12- A Patient's Perspective

We are not yet done with our breast cancer series, but we could not wait to share this incredibly personal conversation with a patient with a recent breast cancer diagnosis. This week, we sit down with Kaele Leonard, who herself is a Pulmonary/Critical Care fellow at Vanderbilt University Medical Center who was diagnosed with breast cancer in her early 30s.

As physicians, we don’t always get to hear what the journey through diagnosis, treatment, and follow up looks like from a patient’s perspective. We are so grateful to Dr. Leonard for opening up about this with us.

Episode 066: Breast Cancer Series, Pt. 11-Metastatic HER2+ Breast Cancer

This week, we continue our discussion about metastatic breast cancer, focusing on HER2+ disease.

Episode 065: Breast Cancer Series, Pt. 10-ER+, Metastatic Breast Cancer

After several weeks of covering localized disease, this week, we shift our discussion to metastatic breast cancer, focusing first on ER+ disease.

Episode 064: Breast Cancer Series, Pt. 9-Triple Negative, Early Stage Breast Cancer

This week, we round out our discussion on the early stage breast cancer, turning our attention to the triple negative subtype. Once again, there are a lot of trials and data, but be sure to check out the show notes for the highlights!

Episode 063: Breast Cancer Series, Pt. 8-HER2+, Early Stage Breast Cancer

We continue on our journey through early stage breast cancer, this time turning our attention to HER2+ disease. There is a lot of data in this episode, as you will both hear and see. To make this easier, we highlight key takeaways to make understanding this even easier.

Episode 062: “Paging Heme/Onc: Updates from ASCO 2023” - Management of NSCLC and KEYNOTE 671

This week’s episode is part 4 of 5 of a joint mini-series with our friends Two Onc Docs. In today’s episode, we will be recapping the current treatment of resectable NSCLC and discussing KEYNOTE 671, which was presented at ASCO 2023, looking at neoadjuvant chemo+immunotherapy followed by adjuvant immunotherapy. We also discuss the use of the “interaction test,” “multiplicity,” and it’s important role in understanding subgroup analyses.

Episode 061: “Paging Heme/Onc: Updates from ASCO 2023” - Classical Hodgkin’s Lymphoma and SWOG 1826

This week’s episode is part 2 of 5 of a joint mini-series with our friends Two Onc Docs. In today’s episode, we recap the current treatment of classical hodgkin’s lymphoma and then dive into the the SWOG 1826 plenary session abstract from the ASCO 2023 annual meeting. We also cover the concept of “p-values” and what it means when trials say “the median was not reached.”

Episode 060: Heme Consults Series - Fundamentals of Transfusion Medicine

We are taking a small pause from our breast cancer series to discuss an important topic that is so critical to understand for clinical practice, no matter what discipline of medicine you are in: the fundamentals of transfusion medicine. This topic often shows up quite frequently on board exams, as well. In this episode, we talk about terms such as “type and screen” and more.

Special Feature: Paging Heme/Onc: Updates from ASCO 2023 - A Collaborative Series!

The teams at Two Onc Docs and The Fellow on Call are teaming up for this special series!

Each episode will focus on a single abstract, poster, or oral presentation from ASCO 2023, and will feature a quick review of any guidelines and management pointers relevant to the disease state under study, followed by an overview of the study design and findings, and finally a discussion of the implications of the research on clinical practice.

We expect to release episodes on June 12, 14, 19, 21, and 26. Episodes will be released alternating between our two podcasts, so make sure you’re subscribed to both!

Follow Two Onc Docs on Twitter: www.twitter.com/twooncdocs

Follow The Fellow on Call on Twitter: www.twitter.com/thefellowoncall

Episode 058: Breast Cancer Series,Pt. 7-ER+, Early Stage Breast Cancer (con’t)

This week, we continue discussing the management of early stage ER+/HER2- breast cancer. If you have not done so already, be sure to check out Episode 057 for the first part of this discussion.

Episode 057: Breast Cancer Series,Pt. 6-ER+, Early Stage Breast Cancer

After several weeks of incredible discussions with our special guests, it’s time that we dive into the medical oncology regarding breast cancer. We start our discussion with the first of our two-part discussion on early stage (AKA non-metastatic) ER+/HER2- breast cancer.

Episode 056: Breast Cancer Series, Pt. 5-Breast Cancer Pharmacology

So much incredible progress has been made in the management and treatment of breast cancer, largely thanks to advances in available therapies and drugs. A good understanding of pharmacology is key to selecting the correct regimen and providing counseling to your patients. This week, are so fortunate to be joined by special guest Dr. Danielle Roman, PharmD, who is an Oncology Clinical Pharmacy Specialist at West Penn Allegheny Oncology Network in Pennsylvania, as she helps us navigate breast cancer pharmacology.

Episode 055: Breast Cancer Series, Pt. 4-Surgical management for breast cancer

Surgery plays a pivotal role in the management of breast cancer, particularly in early stages of disease. This week, we are joined by special guest Dr. Carla Fisher, Associate Professor and Medical Director of Breast Surgical Oncology at Indiana University School of Medicine.

Episode 054: Breast Cancer Series, Pt. 3-Breast Cancer Vocabulary

The language of breast cancer can be confusing and very technical. In this episode, we help you learn and understand so many important words and phrases that have important implications on diagnosis and management. Understanding these will not only help you learn more about breast cancer, but it will also ensure you are better able to communicate the lingo to your patients!